Fluorine in PDB 8tzf: Structure of Full Length LRRK2 Bound to Gzd-824 (I2020T Mutant)

The binding sites of Fluorine atom in the Structure of Full Length LRRK2 Bound to Gzd-824 (I2020T Mutant) (pdb code 8tzf). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Structure of Full Length LRRK2 Bound to Gzd-824 (I2020T Mutant), PDB code: 8tzf:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in the Structure of Full Length LRRK2 Bound to Gzd-824 (I2020T Mutant)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of Full Length LRRK2 Bound to Gzd-824 (I2020T Mutant) within 5.0Å range: probe atom residue distance (Å) B Occ A:F2602 b:107.1 occ:1.00 F26 A:T3X2602 0.0 107.1 1.0 C25 A:T3X2602 1.4 102.8 1.0 F27 A:T3X2602 2.2 102.6 1.0 F28 A:T3X2602 2.2 103.4 1.0 C13 A:T3X2602 2.4 102.9 1.0 C12 A:T3X2602 2.7 102.7 1.0 CD2 A:LEU1932 3.2 57.0 1.0 C14 A:T3X2602 3.7 103.2 1.0 O A:ILE2015 4.0 50.2 1.0 C11 A:T3X2602 4.0 98.4 1.0 CG2 A:ILE1933 4.1 41.1 1.0 C A:ILE2015 4.3 42.4 1.0 C17 A:T3X2602 4.4 100.7 1.0 CA A:ALA2016 4.4 37.6 1.0 N A:ALA2016 4.5 47.5 1.0 N A:ILE1933 4.5 35.4 1.0 CG A:LEU1932 4.6 46.2 1.0 CB A:ILE2015 4.6 28.8 1.0 O09 A:T3X2602 4.6 99.5 1.0 N A:ASP2017 4.8 69.3 1.0 C15 A:T3X2602 4.8 105.7 1.0 C A:ALA2016 4.8 55.5 1.0 N10 A:T3X2602 4.9 94.6 1.0 C16 A:T3X2602 4.9 102.1 1.0 CB A:LEU1932 4.9 37.9 1.0 CE2 A:TYR1992 4.9 78.6 1.0 CB A:ILE1933 5.0 34.2 1.0 O A:ILE1933 5.0 68.9 1.0

Fluorine binding site 2 out of 3 in the Structure of Full Length LRRK2 Bound to Gzd-824 (I2020T Mutant)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Structure of Full Length LRRK2 Bound to Gzd-824 (I2020T Mutant) within 5.0Å range: probe atom residue distance (Å) B Occ A:F2602 b:102.6 occ:1.00 F27 A:T3X2602 0.0 102.6 1.0 C25 A:T3X2602 1.4 102.8 1.0 F26 A:T3X2602 2.2 107.1 1.0 F28 A:T3X2602 2.2 103.4 1.0 C13 A:T3X2602 2.4 102.9 1.0 C14 A:T3X2602 3.0 103.2 1.0 C17 A:T3X2602 3.0 100.7 1.0 CD2 A:LEU1932 3.2 57.0 1.0 CD1 A:LEU1927 3.2 81.0 1.0 C12 A:T3X2602 3.5 102.7 1.0 CD2 A:LEU1985 4.1 72.2 1.0 CD1 A:LEU1932 4.2 51.1 1.0 CG A:LEU1932 4.3 46.2 1.0 C15 A:T3X2602 4.3 105.7 1.0 N18 A:T3X2602 4.3 104.0 1.0 CD1 A:LEU1985 4.4 70.1 1.0 CG A:LEU1927 4.6 74.0 1.0 CG A:LEU1985 4.7 64.8 1.0 C11 A:T3X2602 4.7 98.4 1.0 C23 A:T3X2602 4.7 104.9 1.0 CB A:LEU1927 4.8 73.9 1.0 C19 A:T3X2602 4.9 107.8 1.0 C16 A:T3X2602 5.0 102.1 1.0 CB A:LEU1932 5.0 37.9 1.0

Fluorine binding site 3 out of 3 in the Structure of Full Length LRRK2 Bound to Gzd-824 (I2020T Mutant)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Structure of Full Length LRRK2 Bound to Gzd-824 (I2020T Mutant) within 5.0Å range: probe atom residue distance (Å) B Occ A:F2602 b:103.4 occ:1.00 F28 A:T3X2602 0.0 103.4 1.0 C25 A:T3X2602 1.4 102.8 1.0 F26 A:T3X2602 2.2 107.1 1.0 F27 A:T3X2602 2.2 102.6 1.0 C13 A:T3X2602 2.4 102.9 1.0 C14 A:T3X2602 3.1 103.2 1.0 C17 A:T3X2602 3.1 100.7 1.0 CE2 A:TYR1992 3.1 78.6 1.0 C12 A:T3X2602 3.4 102.7 1.0 CD2 A:TYR1992 3.6 79.8 1.0 C23 A:T3X2602 3.8 104.9 1.0 CD2 A:LEU1932 4.0 57.0 1.0 N18 A:T3X2602 4.0 104.0 1.0 CD1 A:LEU1985 4.1 70.1 1.0 CB A:ASP2017 4.2 71.0 1.0 CZ A:TYR1992 4.3 76.5 1.0 C15 A:T3X2602 4.3 105.7 1.0 OH A:TYR1992 4.6 72.8 1.0 C11 A:T3X2602 4.6 98.4 1.0 CG2 A:ILE2015 4.7 42.2 1.0 N A:ASP2017 4.8 69.3 1.0 CB A:ILE2015 4.8 28.8 1.0 C A:ALA2016 4.8 55.5 1.0 CG A:TYR1992 5.0 74.0 1.0 C16 A:T3X2602 5.0 102.1 1.0 C19 A:T3X2602 5.0 107.8 1.0

A.Villagran-Suarez, M.Sanz-Murillo, J.Alegrio-Louro, A.Leschziner. Structure of Full Length LRRK2 Bound to Gzd-824 (I2020T Mutant) To Be Published.