Fluorine in PDB 9ear: CHD1-Nucleosome Complex (Closed State)

All present enzymatic activity of CHD1-Nucleosome Complex (Closed State):
3.6.4.12;

The binding sites of Fluorine atom in the CHD1-Nucleosome Complex (Closed State) (pdb code 9ear). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the CHD1-Nucleosome Complex (Closed State), PDB code: 9ear:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in the CHD1-Nucleosome Complex (Closed State)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of CHD1-Nucleosome Complex (Closed State) within 5.0Å range: probe atom residue distance (Å) B Occ W:F1502 b:26.2 occ:1.00 F1 W:BEF1502 0.0 26.2 1.0 BE W:BEF1502 1.6 30.6 1.0 CZ W:ARG900 2.2 85.6 1.0 O W:GLY870 2.2 89.7 1.0 NH2 W:ARG900 2.3 81.1 1.0 NH1 W:ARG900 2.3 85.2 1.0 NH1 W:ARG897 2.5 86.0 1.0 F3 W:BEF1502 2.5 28.4 1.0 O2B W:ADP1501 2.6 28.6 1.0 F2 W:BEF1502 2.6 38.3 1.0 NE W:ARG900 3.0 83.4 1.0 C W:GLY870 3.1 89.9 1.0 PB W:ADP1501 3.2 32.0 1.0 O1B W:ADP1501 3.2 48.6 1.0 O3A W:ADP1501 3.4 21.0 1.0 CA W:GLY870 3.5 91.2 1.0 CZ W:ARG897 3.6 86.5 1.0 O W:ILE871 3.8 92.8 1.0 CD W:ARG900 3.9 81.7 1.0 NH2 W:ARG897 4.0 86.6 1.0 C W:ILE871 4.1 90.5 1.0 N W:ILE871 4.2 85.2 1.0 N W:GLY870 4.3 91.4 1.0 NZ W:LYS512 4.3 82.5 1.0 N W:ASN872 4.5 86.0 1.0 NE W:ARG897 4.7 87.2 1.0 CA W:ILE871 4.7 85.7 1.0 CA W:ASN872 4.7 82.6 1.0 O3B W:ADP1501 4.7 27.7 1.0 CB W:ASN872 4.9 85.1 1.0 PA W:ADP1501 5.0 24.4 1.0

Fluorine binding site 2 out of 3 in the CHD1-Nucleosome Complex (Closed State)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of CHD1-Nucleosome Complex (Closed State) within 5.0Å range: probe atom residue distance (Å) B Occ W:F1502 b:38.3 occ:1.00 F2 W:BEF1502 0.0 38.3 1.0 BE W:BEF1502 1.6 30.6 1.0 NH1 W:ARG900 2.3 85.2 1.0 F3 W:BEF1502 2.6 28.4 1.0 F1 W:BEF1502 2.6 26.2 1.0 NZ W:LYS512 2.9 82.5 1.0 O2B W:ADP1501 2.9 28.6 1.0 NH2 W:ARG897 2.9 86.6 1.0 NH2 W:ARG900 2.9 81.1 1.0 CZ W:ARG900 3.0 85.6 1.0 NH1 W:ARG897 3.0 86.0 1.0 CZ W:ARG897 3.4 86.5 1.0 CB W:MET508 3.7 91.0 1.0 N W:GLY509 3.7 86.1 1.0 CE W:LYS512 3.7 86.8 1.0 CG W:MET508 3.8 92.5 1.0 CA W:MET508 3.8 89.2 1.0 C W:MET508 4.2 90.3 1.0 PB W:ADP1501 4.3 32.0 1.0 NE W:ARG900 4.3 83.4 1.0 OE1 W:GLN893 4.4 86.9 1.0 O W:GLY870 4.6 89.7 1.0 CA W:GLY509 4.6 86.3 1.0 CA W:GLY870 4.7 91.2 1.0 O1B W:ADP1501 4.7 48.6 1.0 NE W:ARG897 4.7 87.2 1.0 CD W:LYS512 4.9 86.5 1.0 N W:GLY870 5.0 91.4 1.0

Fluorine binding site 3 out of 3 in the CHD1-Nucleosome Complex (Closed State)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of CHD1-Nucleosome Complex (Closed State) within 5.0Å range: probe atom residue distance (Å) B Occ W:F1502 b:28.4 occ:1.00 F3 W:BEF1502 0.0 28.4 1.0 BE W:BEF1502 1.5 30.6 1.0 F1 W:BEF1502 2.5 26.2 1.0 F2 W:BEF1502 2.6 38.3 1.0 CA W:GLY870 2.8 91.2 1.0 O2B W:ADP1501 3.0 28.6 1.0 O1B W:ADP1501 3.1 48.6 1.0 NH1 W:ARG897 3.2 86.0 1.0 O W:GLY870 3.3 89.7 1.0 NZ W:LYS512 3.5 82.5 1.0 C W:GLY870 3.5 89.9 1.0 N W:GLY870 3.5 91.4 1.0 PB W:ADP1501 3.6 32.0 1.0 CE W:LYS512 3.7 86.8 1.0 NH2 W:ARG900 3.9 81.1 1.0 NH1 W:ARG900 4.1 85.2 1.0 CZ W:ARG897 4.2 86.5 1.0 NH2 W:ARG897 4.3 86.6 1.0 CZ W:ARG900 4.3 85.6 1.0 O3A W:ADP1501 4.7 21.0 1.0 O3B W:ADP1501 4.7 27.7 1.0 OE1 W:GLN893 4.7 86.9 1.0 N W:ILE871 4.8 85.2 1.0 C W:LEU869 4.8 90.7 1.0

A.M.James, L.Farnung. Structural Basis of Human CHD1 Nucleosome Recruitment and Pausing Mol.Cell 2025.
ISSN: ISSN 1097-2765
DOI: 10.1016/J.MOLCEL.2025.04.020