Fluorine in PDB 9jf9: Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation
Enzymatic activity of Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation
All present enzymatic activity of Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation:
2.7.10.1;
Fluorine Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
12;
Binding sites:
The binding sites of Fluorine atom in the Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation
(pdb code 9jf9). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 12 binding sites of Fluorine where determined in the
Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation, PDB code: 9jf9:
Jump to Fluorine binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Fluorine binding site 1 out
of 12 in 9jf9
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Fluorine Binding Sites List in 9jf9
Fluorine binding site 1 out
of 12 in the Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation
 Mono view
 Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F2
b:404.7
occ:1.00
|
F
|
C:AF22
|
0.0
|
404.7
|
1.0
|
C2'
|
C:AF22
|
1.4
|
404.7
|
1.0
|
C3'
|
C:AF22
|
2.2
|
404.7
|
1.0
|
O3'
|
C:AF22
|
2.3
|
404.7
|
1.0
|
C1'
|
C:AF22
|
2.5
|
404.7
|
1.0
|
C4'
|
C:AF22
|
3.4
|
404.7
|
1.0
|
N9
|
C:AF22
|
3.4
|
404.7
|
1.0
|
P
|
C:DUZ3
|
3.4
|
332.2
|
1.0
|
OP2
|
C:DUZ3
|
3.4
|
332.2
|
1.0
|
O4'
|
C:DUZ3
|
3.4
|
332.2
|
1.0
|
O4'
|
C:AF22
|
3.4
|
404.7
|
1.0
|
O22
|
C:DUZ3
|
3.5
|
332.2
|
1.0
|
C5'
|
C:DUZ3
|
3.7
|
332.2
|
1.0
|
C6
|
C:DUZ3
|
3.7
|
332.2
|
1.0
|
C26
|
C:85Y20
|
3.8
|
270.0
|
1.0
|
C30
|
C:85Y20
|
3.9
|
270.0
|
1.0
|
C8
|
C:AF22
|
4.0
|
404.7
|
1.0
|
C4'
|
C:DUZ3
|
4.1
|
332.2
|
1.0
|
O5'
|
C:DUZ3
|
4.1
|
332.2
|
1.0
|
C27
|
C:85Y20
|
4.1
|
270.0
|
1.0
|
C25
|
C:85Y20
|
4.2
|
270.0
|
1.0
|
C31
|
C:85Y20
|
4.2
|
270.0
|
1.0
|
C21
|
C:DUZ3
|
4.3
|
332.2
|
1.0
|
C4
|
C:AF22
|
4.3
|
404.7
|
1.0
|
C5
|
C:DUZ3
|
4.4
|
332.2
|
1.0
|
C33
|
C:85Y20
|
4.5
|
270.0
|
1.0
|
C32
|
C:85Y20
|
4.5
|
270.0
|
1.0
|
C5'
|
C:AF22
|
4.5
|
404.7
|
1.0
|
N1
|
C:DUZ3
|
4.6
|
332.2
|
1.0
|
OP1
|
C:DUZ3
|
4.6
|
332.2
|
1.0
|
C1'
|
C:DUZ3
|
4.7
|
332.2
|
1.0
|
O5'
|
C:AF22
|
4.7
|
404.7
|
1.0
|
C28
|
C:85Y20
|
4.7
|
270.0
|
1.0
|
C24
|
C:85Y20
|
4.8
|
270.0
|
1.0
|
N3
|
C:AF22
|
4.8
|
404.7
|
1.0
|
|
Fluorine binding site 2 out
of 12 in 9jf9
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Fluorine Binding Sites List in 9jf9
Fluorine binding site 2 out
of 12 in the Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation
 Mono view
 Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F6
b:270.0
occ:1.00
|
F2'
|
C:CFZ6
|
0.0
|
270.0
|
1.0
|
C2'
|
C:CFZ6
|
1.4
|
270.0
|
1.0
|
C3'
|
C:CFZ6
|
2.2
|
270.0
|
1.0
|
OP2
|
C:DG7
|
2.5
|
222.2
|
1.0
|
O3'
|
C:CFZ6
|
2.6
|
270.0
|
1.0
|
C1'
|
C:CFZ6
|
2.6
|
270.0
|
1.0
|
C8
|
C:DG7
|
2.8
|
222.2
|
1.0
|
P
|
C:DG7
|
3.1
|
222.2
|
1.0
|
N7
|
C:DG7
|
3.2
|
222.2
|
1.0
|
N1
|
C:CFZ6
|
3.3
|
270.0
|
1.0
|
C6
|
C:CFZ6
|
3.5
|
270.0
|
1.0
|
C4'
|
C:CFZ6
|
3.5
|
270.0
|
1.0
|
O4'
|
C:CFZ6
|
3.6
|
270.0
|
1.0
|
N9
|
C:DG7
|
4.0
|
222.2
|
1.0
|
OP1
|
C:DG7
|
4.0
|
222.2
|
1.0
|
C5'
|
C:CFZ6
|
4.2
|
270.0
|
1.0
|
O5'
|
C:CFZ6
|
4.3
|
270.0
|
1.0
|
O5'
|
C:DG7
|
4.3
|
222.2
|
1.0
|
C5
|
C:DG7
|
4.4
|
222.2
|
1.0
|
C2
|
C:CFZ6
|
4.5
|
270.0
|
1.0
|
C2'
|
C:DG7
|
4.6
|
222.2
|
1.0
|
C1'
|
C:DG7
|
4.7
|
222.2
|
1.0
|
O4'
|
C:DG7
|
4.7
|
222.2
|
1.0
|
C5'
|
C:DG7
|
4.7
|
222.2
|
1.0
|
C5
|
C:CFZ6
|
4.8
|
270.0
|
1.0
|
O2P
|
C:CFZ6
|
4.8
|
270.0
|
1.0
|
C4
|
C:DG7
|
4.8
|
222.2
|
1.0
|
O2
|
C:CFZ6
|
4.9
|
270.0
|
1.0
|
|
Fluorine binding site 3 out
of 12 in 9jf9
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Fluorine Binding Sites List in 9jf9
Fluorine binding site 3 out
of 12 in the Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation
 Mono view
 Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F8
b:270.0
occ:1.00
|
F2'
|
C:CFZ8
|
0.0
|
270.0
|
1.0
|
C2'
|
C:CFZ8
|
1.4
|
270.0
|
1.0
|
C3'
|
C:CFZ8
|
2.2
|
270.0
|
1.0
|
O3'
|
C:CFZ8
|
2.3
|
270.0
|
1.0
|
C1'
|
C:CFZ8
|
2.5
|
270.0
|
1.0
|
O5'
|
C:DA9
|
2.8
|
194.9
|
1.0
|
P
|
C:DA9
|
3.1
|
194.9
|
1.0
|
CD2
|
A:PHE39
|
3.2
|
212.2
|
1.0
|
OH
|
A:TYR67
|
3.4
|
223.2
|
1.0
|
N1
|
C:CFZ8
|
3.4
|
270.0
|
1.0
|
C6
|
C:CFZ8
|
3.4
|
270.0
|
1.0
|
C4'
|
C:CFZ8
|
3.4
|
270.0
|
1.0
|
O4'
|
C:CFZ8
|
3.5
|
270.0
|
1.0
|
CE2
|
A:PHE39
|
3.6
|
212.2
|
1.0
|
OP2
|
C:DA9
|
3.8
|
194.9
|
1.0
|
CZ
|
A:TYR67
|
4.0
|
223.2
|
1.0
|
C5'
|
C:DA9
|
4.0
|
194.9
|
1.0
|
CE2
|
A:TYR67
|
4.1
|
223.2
|
1.0
|
OP1
|
C:DA9
|
4.3
|
194.9
|
1.0
|
CG
|
A:PHE39
|
4.4
|
212.2
|
1.0
|
C5'
|
C:CFZ8
|
4.5
|
270.0
|
1.0
|
C32
|
C:85Y10
|
4.5
|
162.1
|
1.0
|
C31
|
C:85Y10
|
4.5
|
162.1
|
1.0
|
CB
|
A:PHE39
|
4.8
|
212.2
|
1.0
|
C2
|
C:CFZ8
|
4.8
|
270.0
|
1.0
|
C5
|
C:CFZ8
|
4.8
|
270.0
|
1.0
|
CZ
|
A:PHE39
|
4.9
|
212.2
|
1.0
|
CE1
|
A:TYR67
|
5.0
|
223.2
|
1.0
|
C2'
|
C:DG7
|
5.0
|
222.2
|
1.0
|
|
Fluorine binding site 4 out
of 12 in 9jf9
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Fluorine Binding Sites List in 9jf9
Fluorine binding site 4 out
of 12 in the Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation
 Mono view
 Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F12
b:270.0
occ:1.00
|
F
|
C:AF212
|
0.0
|
270.0
|
1.0
|
C2'
|
C:AF212
|
1.4
|
270.0
|
1.0
|
C3'
|
C:AF212
|
2.3
|
270.0
|
1.0
|
O3'
|
C:AF212
|
2.4
|
270.0
|
1.0
|
C1'
|
C:AF212
|
2.5
|
270.0
|
1.0
|
OP2
|
C:OMG13
|
2.8
|
190.6
|
1.0
|
P
|
C:OMG13
|
3.1
|
190.6
|
1.0
|
N9
|
C:AF212
|
3.3
|
270.0
|
1.0
|
C4'
|
C:AF212
|
3.4
|
270.0
|
1.0
|
O4'
|
C:AF212
|
3.5
|
270.0
|
1.0
|
OP1
|
C:OMG13
|
3.8
|
190.6
|
1.0
|
C4
|
C:AF212
|
4.0
|
270.0
|
1.0
|
C8
|
C:AF212
|
4.0
|
270.0
|
1.0
|
N3
|
C:AF212
|
4.3
|
270.0
|
1.0
|
O5'
|
C:OMG13
|
4.4
|
190.6
|
1.0
|
C5'
|
C:AF212
|
4.6
|
270.0
|
1.0
|
C5
|
C:AF212
|
4.9
|
270.0
|
1.0
|
N7
|
C:AF212
|
5.0
|
270.0
|
1.0
|
|
Fluorine binding site 5 out
of 12 in 9jf9
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Fluorine Binding Sites List in 9jf9
Fluorine binding site 5 out
of 12 in the Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation
 Mono view
 Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 5 of Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F19
b:275.5
occ:1.00
|
F
|
C:AF219
|
0.0
|
275.5
|
1.0
|
C2'
|
C:AF219
|
1.4
|
275.5
|
1.0
|
C3'
|
C:AF219
|
2.2
|
275.5
|
1.0
|
O3'
|
C:AF219
|
2.4
|
275.5
|
1.0
|
C1'
|
C:AF219
|
2.5
|
275.5
|
1.0
|
N9
|
C:AF219
|
3.2
|
275.5
|
1.0
|
C4'
|
C:AF219
|
3.5
|
275.5
|
1.0
|
P
|
C:85Y20
|
3.5
|
270.0
|
1.0
|
O4'
|
C:AF219
|
3.5
|
275.5
|
1.0
|
OP2
|
C:85Y20
|
3.6
|
270.0
|
1.0
|
C4
|
C:AF219
|
3.7
|
275.5
|
1.0
|
CD2
|
B:LEU486
|
3.8
|
161.6
|
1.0
|
N3
|
C:AF219
|
3.9
|
275.5
|
1.0
|
OP1
|
C:85Y20
|
4.0
|
270.0
|
1.0
|
C8
|
C:AF219
|
4.0
|
275.5
|
1.0
|
CG
|
B:LEU486
|
4.4
|
161.6
|
1.0
|
C5'
|
C:AF219
|
4.5
|
275.5
|
1.0
|
C5
|
C:AF219
|
4.7
|
275.5
|
1.0
|
N4
|
C:OMC21
|
4.8
|
210.7
|
1.0
|
N7
|
C:AF219
|
4.9
|
275.5
|
1.0
|
O5'
|
C:85Y20
|
4.9
|
270.0
|
1.0
|
CD2
|
B:LEU552
|
5.0
|
124.1
|
1.0
|
C2
|
C:AF219
|
5.0
|
275.5
|
1.0
|
|
Fluorine binding site 6 out
of 12 in 9jf9
Go back to
Fluorine Binding Sites List in 9jf9
Fluorine binding site 6 out
of 12 in the Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation
 Mono view
 Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 6 of Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F22
b:270.0
occ:1.00
|
F2'
|
C:CFZ22
|
0.0
|
270.0
|
1.0
|
C2'
|
C:CFZ22
|
1.4
|
270.0
|
1.0
|
C3'
|
C:CFZ22
|
2.2
|
270.0
|
1.0
|
O3'
|
C:CFZ22
|
2.3
|
270.0
|
1.0
|
O4'
|
C:DG23
|
2.3
|
173.2
|
1.0
|
C1'
|
C:CFZ22
|
2.5
|
270.0
|
1.0
|
O5'
|
C:DG23
|
2.7
|
173.2
|
1.0
|
O2
|
C:CFZ22
|
2.9
|
270.0
|
1.0
|
C8
|
C:DG23
|
2.9
|
173.2
|
1.0
|
C5'
|
C:DG23
|
3.0
|
173.2
|
1.0
|
P
|
C:DG23
|
3.1
|
173.2
|
1.0
|
N1
|
C:CFZ22
|
3.2
|
270.0
|
1.0
|
C4'
|
C:DG23
|
3.2
|
173.2
|
1.0
|
C2
|
C:CFZ22
|
3.3
|
270.0
|
1.0
|
N9
|
C:DG23
|
3.4
|
173.2
|
1.0
|
C1'
|
C:DG23
|
3.4
|
173.2
|
1.0
|
C4'
|
C:CFZ22
|
3.4
|
270.0
|
1.0
|
O4'
|
C:CFZ22
|
3.5
|
270.0
|
1.0
|
OP2
|
C:DG23
|
3.5
|
173.2
|
1.0
|
N7
|
C:DG23
|
3.9
|
173.2
|
1.0
|
C3'
|
C:DG23
|
4.1
|
173.2
|
1.0
|
OP1
|
C:DG23
|
4.3
|
173.2
|
1.0
|
C2'
|
C:DG23
|
4.4
|
173.2
|
1.0
|
C6
|
C:CFZ22
|
4.4
|
270.0
|
1.0
|
C4
|
C:DG23
|
4.5
|
173.2
|
1.0
|
C5'
|
C:CFZ22
|
4.6
|
270.0
|
1.0
|
N3
|
C:CFZ22
|
4.6
|
270.0
|
1.0
|
O5'
|
C:CFZ22
|
4.6
|
270.0
|
1.0
|
C5
|
C:DG23
|
4.7
|
173.2
|
1.0
|
|
Fluorine binding site 7 out
of 12 in 9jf9
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Fluorine Binding Sites List in 9jf9
Fluorine binding site 7 out
of 12 in the Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation
 Mono view
 Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 7 of Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:F2
b:317.4
occ:1.00
|
F
|
D:AF22
|
0.0
|
317.4
|
1.0
|
C2'
|
D:AF22
|
1.4
|
317.4
|
1.0
|
C3'
|
D:AF22
|
2.2
|
317.4
|
1.0
|
O3'
|
D:AF22
|
2.3
|
317.4
|
1.0
|
C1'
|
D:AF22
|
2.5
|
317.4
|
1.0
|
C4'
|
D:AF22
|
3.2
|
317.4
|
1.0
|
O4'
|
D:DUZ3
|
3.4
|
301.7
|
1.0
|
C30
|
D:85Y20
|
3.4
|
188.0
|
1.0
|
O4'
|
D:AF22
|
3.4
|
317.4
|
1.0
|
N9
|
D:AF22
|
3.5
|
317.4
|
1.0
|
C26
|
D:85Y20
|
3.5
|
188.0
|
1.0
|
O22
|
D:DUZ3
|
3.7
|
301.7
|
1.0
|
C31
|
D:85Y20
|
3.7
|
188.0
|
1.0
|
P
|
D:DUZ3
|
3.7
|
301.7
|
1.0
|
C6
|
D:DUZ3
|
3.8
|
301.7
|
1.0
|
C5'
|
D:DUZ3
|
4.0
|
301.7
|
1.0
|
C25
|
D:85Y20
|
4.0
|
188.0
|
1.0
|
C27
|
D:85Y20
|
4.0
|
188.0
|
1.0
|
OP2
|
D:DUZ3
|
4.0
|
301.7
|
1.0
|
C4'
|
D:DUZ3
|
4.1
|
301.7
|
1.0
|
C32
|
D:85Y20
|
4.2
|
188.0
|
1.0
|
C8
|
D:AF22
|
4.2
|
317.4
|
1.0
|
C4
|
D:AF22
|
4.2
|
317.4
|
1.0
|
C33
|
D:85Y20
|
4.3
|
188.0
|
1.0
|
O5'
|
D:DUZ3
|
4.4
|
301.7
|
1.0
|
C5'
|
D:AF22
|
4.5
|
317.4
|
1.0
|
C21
|
D:DUZ3
|
4.5
|
301.7
|
1.0
|
N3
|
D:AF22
|
4.6
|
317.4
|
1.0
|
C5
|
D:DUZ3
|
4.7
|
301.7
|
1.0
|
C1'
|
D:DUZ3
|
4.7
|
301.7
|
1.0
|
OP1
|
D:DUZ3
|
4.8
|
301.7
|
1.0
|
N1
|
D:DUZ3
|
4.8
|
301.7
|
1.0
|
C24
|
D:85Y20
|
4.8
|
188.0
|
1.0
|
C28
|
D:85Y20
|
4.8
|
188.0
|
1.0
|
O5'
|
D:AF22
|
4.8
|
317.4
|
1.0
|
|
Fluorine binding site 8 out
of 12 in 9jf9
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Fluorine Binding Sites List in 9jf9
Fluorine binding site 8 out
of 12 in the Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation
 Mono view
 Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 8 of Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:F6
b:270.0
occ:1.00
|
F2'
|
D:CFZ6
|
0.0
|
270.0
|
1.0
|
C2'
|
D:CFZ6
|
1.4
|
270.0
|
1.0
|
C3'
|
D:CFZ6
|
2.2
|
270.0
|
1.0
|
O3'
|
D:CFZ6
|
2.4
|
270.0
|
1.0
|
C1'
|
D:CFZ6
|
2.6
|
270.0
|
1.0
|
C8
|
D:DG7
|
3.0
|
226.1
|
1.0
|
N1
|
D:CFZ6
|
3.1
|
270.0
|
1.0
|
C6
|
D:CFZ6
|
3.3
|
270.0
|
1.0
|
OP2
|
D:DG7
|
3.3
|
226.1
|
1.0
|
N7
|
D:DG7
|
3.4
|
226.1
|
1.0
|
P
|
D:DG7
|
3.5
|
226.1
|
1.0
|
C4'
|
D:CFZ6
|
3.5
|
270.0
|
1.0
|
O4'
|
D:CFZ6
|
3.6
|
270.0
|
1.0
|
O2P
|
D:CFZ6
|
3.9
|
270.0
|
1.0
|
N9
|
D:DG7
|
4.1
|
226.1
|
1.0
|
C5'
|
D:CFZ6
|
4.3
|
270.0
|
1.0
|
O5'
|
D:CFZ6
|
4.3
|
270.0
|
1.0
|
C2
|
D:CFZ6
|
4.4
|
270.0
|
1.0
|
O4'
|
D:DG7
|
4.5
|
226.1
|
1.0
|
O5'
|
D:DG7
|
4.5
|
226.1
|
1.0
|
OP1
|
D:DG7
|
4.5
|
226.1
|
1.0
|
C5
|
D:CFZ6
|
4.6
|
270.0
|
1.0
|
C5
|
D:DG7
|
4.6
|
226.1
|
1.0
|
C1'
|
D:DG7
|
4.7
|
226.1
|
1.0
|
P
|
D:CFZ6
|
4.8
|
270.0
|
1.0
|
C2'
|
D:DG7
|
4.8
|
226.1
|
1.0
|
O2
|
D:CFZ6
|
4.8
|
270.0
|
1.0
|
|
Fluorine binding site 9 out
of 12 in 9jf9
Go back to
Fluorine Binding Sites List in 9jf9
Fluorine binding site 9 out
of 12 in the Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation
 Mono view
 Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 9 of Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:F8
b:270.0
occ:1.00
|
F2'
|
D:CFZ8
|
0.0
|
270.0
|
1.0
|
C2'
|
D:CFZ8
|
1.4
|
270.0
|
1.0
|
C3'
|
D:CFZ8
|
2.2
|
270.0
|
1.0
|
O3'
|
D:CFZ8
|
2.3
|
270.0
|
1.0
|
C1'
|
D:CFZ8
|
2.5
|
270.0
|
1.0
|
O5'
|
D:DA9
|
2.9
|
270.0
|
1.0
|
P
|
D:DA9
|
3.1
|
270.0
|
1.0
|
OH
|
B:TYR67
|
3.2
|
267.9
|
1.0
|
C6
|
D:CFZ8
|
3.3
|
270.0
|
1.0
|
N1
|
D:CFZ8
|
3.4
|
270.0
|
1.0
|
C4'
|
D:CFZ8
|
3.4
|
270.0
|
1.0
|
O4'
|
D:CFZ8
|
3.5
|
270.0
|
1.0
|
OP2
|
D:DA9
|
3.7
|
270.0
|
1.0
|
CZ
|
B:TYR67
|
3.7
|
267.9
|
1.0
|
CE2
|
B:TYR67
|
3.8
|
267.9
|
1.0
|
C5'
|
D:DA9
|
3.9
|
270.0
|
1.0
|
C31
|
D:85Y10
|
4.1
|
270.0
|
1.0
|
C32
|
D:85Y10
|
4.1
|
270.0
|
1.0
|
OP1
|
D:DA9
|
4.4
|
270.0
|
1.0
|
C5'
|
D:CFZ8
|
4.5
|
270.0
|
1.0
|
C2'
|
D:DG7
|
4.5
|
226.1
|
1.0
|
C5
|
D:CFZ8
|
4.8
|
270.0
|
1.0
|
CE1
|
B:TYR67
|
4.8
|
267.9
|
1.0
|
C2
|
D:CFZ8
|
4.9
|
270.0
|
1.0
|
CD2
|
B:TYR67
|
4.9
|
267.9
|
1.0
|
O3'
|
D:DG7
|
4.9
|
226.1
|
1.0
|
C30
|
D:85Y10
|
5.0
|
270.0
|
1.0
|
|
Fluorine binding site 10 out
of 12 in 9jf9
Go back to
Fluorine Binding Sites List in 9jf9
Fluorine binding site 10 out
of 12 in the Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation
 Mono view
 Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 10 of Human Insulin Receptor Bound with A62-Dimer, Pseudo-Arrowhead Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:F12
b:270.0
occ:1.00
|
F
|
D:AF212
|
0.0
|
270.0
|
1.0
|
C2'
|
D:AF212
|
1.4
|
270.0
|
1.0
|
C3'
|
D:AF212
|
2.2
|
270.0
|
1.0
|
O3'
|
D:AF212
|
2.4
|
270.0
|
1.0
|
C1'
|
D:AF212
|
2.5
|
270.0
|
1.0
|
OP2
|
D:OMG13
|
2.8
|
270.0
|
1.0
|
NE
|
A:ARG554
|
3.0
|
192.4
|
1.0
|
P
|
D:OMG13
|
3.1
|
270.0
|
1.0
|
NH2
|
A:ARG554
|
3.1
|
192.4
|
1.0
|
N9
|
D:AF212
|
3.3
|
270.0
|
1.0
|
CZ
|
A:ARG554
|
3.4
|
192.4
|
1.0
|
C4'
|
D:AF212
|
3.4
|
270.0
|
1.0
|
O4'
|
D:AF212
|
3.5
|
270.0
|
1.0
|
C8
|
D:AF212
|
3.9
|
270.0
|
1.0
|
OP1
|
D:OMG13
|
3.9
|
270.0
|
1.0
|
CD
|
A:ARG554
|
4.0
|
192.4
|
1.0
|
C4
|
D:AF212
|
4.1
|
270.0
|
1.0
|
O5'
|
D:OMG13
|
4.4
|
270.0
|
1.0
|
C5'
|
D:AF212
|
4.5
|
270.0
|
1.0
|
N3
|
D:AF212
|
4.6
|
270.0
|
1.0
|
NH1
|
A:ARG554
|
4.6
|
192.4
|
1.0
|
OP2
|
D:AF212
|
4.7
|
270.0
|
1.0
|
N7
|
D:AF212
|
4.9
|
270.0
|
1.0
|
O5'
|
D:AF212
|
4.9
|
270.0
|
1.0
|
C5
|
D:AF212
|
5.0
|
270.0
|
1.0
|
|
Reference:
J.Kim,
H.Na,
S.Y.Choi,
E.J.Oh,
H.Lee,
S.H.Ryu,
N.O.Yunn,
Y.Cho.
Structural Mechanism of Insulin Receptor Activation By A Dimeric Aptamer Agonist. Exp.Mol.Med. 2025.
ISSN: ISSN 1226-3613
PubMed: 40603733
DOI: 10.1038/S12276-025-01494-1
Page generated: Mon Aug 4 22:23:31 2025
|