Fluorine in PDB, part 123 (files: 4881-4920),
PDB 5tbo-5tvj
Experimental structures of coordination spheres of Fluorine (F) in bioorganic
molecules from X-Ray and NMR experiments. Coordination spheres were calculated with 5.0 Angstroms radius
around Fluorine atoms. PDB files: 4881-4920 (PDB 5tbo-5tvj).
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5tbo (F: 5) - Crystal Structure of Plasmodium Falciparum Dihydroorotate Dehydrogenase Bound with Inhibitor DSM421
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5tbp (F: 6) - Crystal Structure of Rxr-Alpha Ligand Binding Domain Complexed with Synthetic Modulator K8003
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5tci (F: 5) - Crystal Structure of Tryptophan Synthase From M. Tuberculosis - BRD4592-Bound Form
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5tcj (F: 4) - Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate and BRD4592-Bound Form
Other atoms:
Cs (9);
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5tco (F: 1) - Human P38 Map Kinase in Complex with Dibenzosuberone Compound 1
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5td7 (F: 3) - Crystal Structure of Histone Deacetylase 10
Other atoms:
K (2);
Zn (1);
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5tdi (F: 4) - Crystal Structure of Cathepsin K with A Covalently-Linked Inhibitor at 1.4 Angstrom Resolution.
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5te8 (F: 3) - Crystal Structure of the Midazolam-Bound Human CYP3A4
Other atoms:
Fe (3);
Cl (3);
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5tei (F: 1) - Structure of Human ALDH1A1 with Inhibitor CM039
Other atoms:
Yb (2);
Cl (1);
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5tft (F: 20) - Structure of Cytochrome P450 2D6 (CYP2D6) BACE1 Inhibitor Complex
Other atoms:
Fe (4);
Zn (5);
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5tfu (F: 20) - Structure of Cytochrome P450 2D6 (CYP2D6) BACE1 Inhibitor Complex
Other atoms:
Fe (4);
Zn (5);
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5tgy (F: 240) - uc(Nmr) Structure of Holo-PS1
Other atoms:
Zn (20);
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5ti2 (F: 1) - Crystal Structure of the First Bromodomain of Human BRD4 in Complex with Inhibitor 7635936
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5ti4 (F: 1) - Crystal Structure of the First Bromodomain of Human BRD4 in Complex with Inhibitor 8841871
Other atoms:
Cl (1);
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5ti6 (F: 2) - Crystal Structure of the First Bromodomain of Human BRD4 in Complex with Inhibitor 8841881
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5tkb (F: 16) - Crystal Structure of Human Phosphodiesterase 4D in Complex with A Tetrafluoranline Compound
Other atoms:
Mg (4);
Zn (4);
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5tl8 (F: 2) - Naegleria Fowleri CYP51-Posaconazole Complex
Other atoms:
Fe (1);
Ca (2);
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5tlf (F: 6) - Crystal Structure of the Er-Alpha Ligand-Binding Domain (Y537S) in Complex with the Constrained Way Derivative, 4-(2-(3-Methylbut-2-En- 1-Yl)-7-(Trifluoromethyl)-2H-Indazol-3-Yl)Benzene-1,3-Diol
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5tlp (F: 1) - Crystal Structure of the Er-Alpha Ligand-Binding Domain (Y537S) in Complex with the Obhs-Bsc Analog, 3-Fluorophenyl (1R,2R,4S)-5-(4- Hydroxyphenyl)-6-(4-(2-(Piperidin-1-Yl)Ethoxy)Phenyl)-7- Oxabicyclo[2.2.1]Hept-5-Ene-2-Sulfonate and 3-Methyl-6-Phenyl-3H- Imidazo[4,5-B]Pyridin-2-Amine
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5tlv (F: 4) - Crystal Structure of the Er-Alpha Ligand-Binding Domain (Y537S) in Complex with 4,4'-(Thiophene-2,3-Diyl)Bis(3-Fluorophenol)
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5tly (F: 4) - Crystal Structure of the Er-Alpha Ligand-Binding Domain (Y537S) in Complex with 3,4-Bis(2-Fluoro-4-Hydroxyphenyl)Thiophene 1,1-Dioxide
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5tm1 (F: 4) - Crystal Structure of the Er-Alpha Ligand-Binding Domain (Y537S) in Complex with 2,5-Bis(2-Fluoro-4-Hydroxyphenyl)Thiophene 1-Oxide
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5tmd (F: 1) - Crystal Structure of OS79 From O. Sativa in Complex with U2F and Trichothecene.
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5tn7 (F: 3) - Crystal Structure of the Er-Alpha Ligand-Binding Domain (Y537S) in Complex with (E)-3'-Fluoro-4'-Hydroxy-3-((Hydroxyiminio)Methyl)-[1, 1'-Biphenyl]-4-Olate
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5to8 (F: 3) - Selectivity Switch Between Fak and PYK2: Macrocyclization of Fak Inhibitors Improves PYK2 Potency
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5tob (F: 3) - Selectivity Switch Between Fak and PYK2: Macrocyclization of Fak Inhibitors Improves PYK2 Potency
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5tol (F: 1) - Crystal Structure of Beta-Site App-Cleaving Enzyme 1 Complexed with N- (3-((4AS,7AS)-2-Amino-4,4A,5,6-Tetrahydro-7AH-Furo[2,3-D][1, 3]Thiazin-7A-Yl)-4-Fluorophenyl)-5-Bromo-2-Pyridinecarboxamide
Other atoms:
Br (1);
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5tp9 (F: 3) - Structure of the Human GLUN1/GLUN2A Lbd in Complex with Compound 2 (GNE9178)
Other atoms:
Cl (1);
Ca (1);
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5tpa (F: 3) - Structure of the Human GLUN1/GLUN2A Lbd in Complex with Compound 9 (GNE3500)
Other atoms:
Cl (1);
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5tpg (F: 3) - Optimization of Spirocyclic Proline Tryptophanhydroxylase-1 Inhibitors
Other atoms:
Fe (1);
Cl (1);
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5tq8 (F: 1) - Design and Synthesis of A Pan-Jak Kinase Inhibitor Clinical Candidate (Pf-06263276) Suitable For Inhaled and Topical Delivery For the Treatment of Inflammatory Diseases of the Lungs and Skin
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5tqg (F: 3) - Factor Viia in Complex with the Inhibitor (5R,11R)-11-[(1-Amino-4- Fluoroisoquinolin-6-Yl)Amino]-16-(Cyclopropylsulfonyl)-7-(2,2- Difluoroethoxy)-5,13-Dimethyl-2,13-Diazatricyclo[13.3.1.1~6, 10~]Icosa-1(19),6(20),7,9,15,17-Hexaene-3,12-Dione
Other atoms:
Ca (1);
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5tqh (F: 4) - IDH1 R132H Mutant in Complex with IDH889
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5tr4 (F: 6) - Structure of Ubiquitin Activating Enzyme (UBA1) in Complex with Ubiquitin and Tak-243
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5tr6 (F: 1) - Discovery of Tak-659, An Orally Available Investigational Inhibitor of Spleen Tyrosine Kinase (Syk)
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5trf (F: 5) - MDM2 in Complex with SAR405838
Other atoms:
Cl (10);
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5trg (F: 14) - Structure of Mycobacterium Tuberculosis Proteasome in Complex with N, C-Capped Dipeptide Dplg-2
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5tth (F: 6) - Heterodimeric Spycatcher/Spytag-Fused Zebrafish TRAP1 in Atp/Adp- Hybrid State
Other atoms:
Mg (2);
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5tto (F: 4) - X-Ray Crystal Structure of Ppargamma in Complex with SR1643
Other atoms:
Br (2);
Cl (4);
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5tvj (F: 1) - Crystal Structure of Acetyltransferase Eis From Mycobacterium Tuberculosis in Complex with Coa and Inhibitor 2K*: 1-(4- Fluorophenyl)-2-[2-(4-Methylphenyl)-2-Oxoethyl]Pyrrolo[1,2-A]Pyrazin- 2-Ium
Other atoms:
Cl (1);
Page generated: Mon Aug 4 21:57:53 2025
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