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Atomistry » Fluorine » PDB 8d0f-8dk4 » 8dg6 » |
Fluorine in PDB 8dg6: Scaffold Hopping Via Ring Opening Enables Identification of Acyclic Compounds As New Complement Factor D InhibitorsEnzymatic activity of Scaffold Hopping Via Ring Opening Enables Identification of Acyclic Compounds As New Complement Factor D Inhibitors
All present enzymatic activity of Scaffold Hopping Via Ring Opening Enables Identification of Acyclic Compounds As New Complement Factor D Inhibitors:
3.4.21.46; Protein crystallography data
The structure of Scaffold Hopping Via Ring Opening Enables Identification of Acyclic Compounds As New Complement Factor D Inhibitors, PDB code: 8dg6
was solved by
K.Raman,
Y.S.Babu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8dg6:
The structure of Scaffold Hopping Via Ring Opening Enables Identification of Acyclic Compounds As New Complement Factor D Inhibitors also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Scaffold Hopping Via Ring Opening Enables Identification of Acyclic Compounds As New Complement Factor D Inhibitors
(pdb code 8dg6). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Scaffold Hopping Via Ring Opening Enables Identification of Acyclic Compounds As New Complement Factor D Inhibitors, PDB code: 8dg6: Fluorine binding site 1 out of 1 in 8dg6Go back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Scaffold Hopping Via Ring Opening Enables Identification of Acyclic Compounds As New Complement Factor D Inhibitors
![]() Mono view ![]() Stereo pair view
Reference:
W.Zhang,
M.Wu,
S.Vadlakonda,
L.Juarez,
X.Cheng,
S.Muppa,
V.Chintareddy,
L.Vogeti,
D.Kellogg-Yelder,
J.Williams,
K.Polach,
X.Chen,
K.Raman,
Y.S.Babu,
P.Kotian.
Scaffold Hopping Via Ring Opening Enables Identification of Acyclic Compounds As New Complement Factor D Inhibitors. Bioorg.Med.Chem. V. 74 17034 2022.
Page generated: Wed Jul 16 03:24:28 2025
ISSN: ESSN 1464-3391 PubMed: 36272185 DOI: 10.1016/J.BMC.2022.117034 |
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