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Fluorine in PDB 9jvw: Overall Structure of Human EAAT2 Bound with Inhibitor (Way-213613)

Other elements in 9jvw:

The structure of Overall Structure of Human EAAT2 Bound with Inhibitor (Way-213613) also contains other interesting chemical elements:

Bromine (Br) 3 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Overall Structure of Human EAAT2 Bound with Inhibitor (Way-213613) (pdb code 9jvw). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the Overall Structure of Human EAAT2 Bound with Inhibitor (Way-213613), PDB code: 9jvw:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6;

Fluorine binding site 1 out of 6 in 9jvw

Go back to Fluorine Binding Sites List in 9jvw
Fluorine binding site 1 out of 6 in the Overall Structure of Human EAAT2 Bound with Inhibitor (Way-213613)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Overall Structure of Human EAAT2 Bound with Inhibitor (Way-213613) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1002

b:71.5
occ:1.00
F1 A:GJ01002 0.0 71.5 1.0
C2 A:GJ01002 1.3 71.5 1.0
C3 A:GJ01002 2.3 71.5 1.0
C25 A:GJ01002 2.4 71.5 1.0
F4 A:GJ01002 2.5 71.5 1.0
CG2 A:VAL468 2.9 87.5 1.0
N A:VAL468 3.0 87.5 1.0
C A:LEU467 3.1 88.2 1.0
CB A:LEU467 3.2 88.2 1.0
CA A:VAL468 3.4 87.5 1.0
O A:LEU467 3.5 88.2 1.0
C5 A:GJ01002 3.6 71.5 1.0
C23 A:GJ01002 3.6 71.5 1.0
CA A:LEU467 3.7 88.2 1.0
CB A:VAL468 3.8 87.5 1.0
OH A:TYR404 3.8 75.7 1.0
O A:ILE464 3.8 86.7 1.0
C6 A:GJ01002 4.1 71.5 1.0
OD2 A:ASP471 4.3 89.5 1.0
CG A:LEU467 4.4 88.2 1.0
CD2 A:LEU467 4.4 88.2 1.0
CD1 A:LEU447 4.5 74.6 1.0
CG1 A:ILE464 4.5 86.7 1.0
CG A:ASP471 4.6 89.5 1.0
N A:LEU467 4.6 88.2 1.0
CG1 A:VAL468 4.7 87.5 1.0
CB A:ASP471 4.7 89.5 1.0
C A:VAL468 4.8 87.5 1.0

Fluorine binding site 2 out of 6 in 9jvw

Go back to Fluorine Binding Sites List in 9jvw
Fluorine binding site 2 out of 6 in the Overall Structure of Human EAAT2 Bound with Inhibitor (Way-213613)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Overall Structure of Human EAAT2 Bound with Inhibitor (Way-213613) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1002

b:71.5
occ:1.00
F4 A:GJ01002 0.0 71.5 1.0
C3 A:GJ01002 1.4 71.5 1.0
C2 A:GJ01002 2.3 71.5 1.0
C5 A:GJ01002 2.4 71.5 1.0
F1 A:GJ01002 2.5 71.5 1.0
CG A:MET450 2.8 75.6 1.0
OH A:TYR404 3.2 75.7 1.0
C25 A:GJ01002 3.6 71.5 1.0
C6 A:GJ01002 3.7 71.5 1.0
SD A:MET450 3.7 75.6 1.0
CB A:MET450 3.8 75.6 1.0
CD2 A:LEU467 3.8 88.2 1.0
CE A:MET450 4.0 75.6 1.0
CB A:LEU467 4.1 88.2 1.0
C23 A:GJ01002 4.1 71.5 1.0
CZ A:TYR404 4.2 75.7 1.0
CG1 A:ILE464 4.2 86.7 1.0
CD1 A:ILE464 4.4 86.7 1.0
CE2 A:TYR404 4.5 75.7 1.0
CG A:LEU467 4.5 88.2 1.0
CD1 A:LEU447 4.7 74.6 1.0
O7 A:GJ01002 4.9 71.5 1.0
O A:GLY446 4.9 81.2 1.0

Fluorine binding site 3 out of 6 in 9jvw

Go back to Fluorine Binding Sites List in 9jvw
Fluorine binding site 3 out of 6 in the Overall Structure of Human EAAT2 Bound with Inhibitor (Way-213613)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Overall Structure of Human EAAT2 Bound with Inhibitor (Way-213613) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F1002

b:71.5
occ:1.00
F1 B:GJ01002 0.0 71.5 1.0
C2 B:GJ01002 1.3 71.5 1.0
C3 B:GJ01002 2.3 71.5 1.0
C25 B:GJ01002 2.4 71.5 1.0
F4 B:GJ01002 2.5 71.5 1.0
CG2 B:VAL468 2.9 87.5 1.0
N B:VAL468 3.0 87.5 1.0
C B:LEU467 3.1 88.2 1.0
CB B:LEU467 3.2 88.2 1.0
CA B:VAL468 3.4 87.5 1.0
O B:LEU467 3.5 88.2 1.0
C5 B:GJ01002 3.6 71.5 1.0
C23 B:GJ01002 3.6 71.5 1.0
CA B:LEU467 3.7 88.2 1.0
CB B:VAL468 3.8 87.5 1.0
OH B:TYR404 3.8 75.7 1.0
O B:ILE464 3.8 86.7 1.0
C6 B:GJ01002 4.1 71.5 1.0
OD2 B:ASP471 4.3 89.5 1.0
CG B:LEU467 4.4 88.2 1.0
CD2 B:LEU467 4.4 88.2 1.0
CD1 B:LEU447 4.5 74.6 1.0
CG1 B:ILE464 4.5 86.7 1.0
N B:LEU467 4.6 88.2 1.0
CG B:ASP471 4.6 89.5 1.0
CG1 B:VAL468 4.7 87.5 1.0
CB B:ASP471 4.7 89.5 1.0
C B:VAL468 4.8 87.5 1.0

Fluorine binding site 4 out of 6 in 9jvw

Go back to Fluorine Binding Sites List in 9jvw
Fluorine binding site 4 out of 6 in the Overall Structure of Human EAAT2 Bound with Inhibitor (Way-213613)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Overall Structure of Human EAAT2 Bound with Inhibitor (Way-213613) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F1002

b:71.5
occ:1.00
F4 B:GJ01002 0.0 71.5 1.0
C3 B:GJ01002 1.4 71.5 1.0
C2 B:GJ01002 2.3 71.5 1.0
C5 B:GJ01002 2.4 71.5 1.0
F1 B:GJ01002 2.5 71.5 1.0
CG B:MET450 2.8 75.6 1.0
OH B:TYR404 3.2 75.7 1.0
C25 B:GJ01002 3.6 71.5 1.0
C6 B:GJ01002 3.7 71.5 1.0
SD B:MET450 3.7 75.6 1.0
CB B:MET450 3.8 75.6 1.0
CD2 B:LEU467 3.8 88.2 1.0
CE B:MET450 4.0 75.6 1.0
CB B:LEU467 4.1 88.2 1.0
C23 B:GJ01002 4.1 71.5 1.0
CZ B:TYR404 4.2 75.7 1.0
CG1 B:ILE464 4.2 86.7 1.0
CD1 B:ILE464 4.4 86.7 1.0
CE2 B:TYR404 4.5 75.7 1.0
CG B:LEU467 4.5 88.2 1.0
CD1 B:LEU447 4.7 74.6 1.0
O7 B:GJ01002 4.9 71.5 1.0
O B:GLY446 4.9 81.2 1.0

Fluorine binding site 5 out of 6 in 9jvw

Go back to Fluorine Binding Sites List in 9jvw
Fluorine binding site 5 out of 6 in the Overall Structure of Human EAAT2 Bound with Inhibitor (Way-213613)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Overall Structure of Human EAAT2 Bound with Inhibitor (Way-213613) within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F1002

b:71.5
occ:1.00
F1 C:GJ01002 0.0 71.5 1.0
C2 C:GJ01002 1.3 71.5 1.0
C3 C:GJ01002 2.3 71.5 1.0
C25 C:GJ01002 2.4 71.5 1.0
F4 C:GJ01002 2.5 71.5 1.0
CG2 C:VAL468 2.9 87.5 1.0
N C:VAL468 3.0 87.5 1.0
C C:LEU467 3.1 88.2 1.0
CB C:LEU467 3.2 88.2 1.0
CA C:VAL468 3.4 87.5 1.0
O C:LEU467 3.5 88.2 1.0
C5 C:GJ01002 3.6 71.5 1.0
C23 C:GJ01002 3.6 71.5 1.0
CA C:LEU467 3.7 88.2 1.0
CB C:VAL468 3.8 87.5 1.0
OH C:TYR404 3.8 75.7 1.0
O C:ILE464 3.8 86.7 1.0
C6 C:GJ01002 4.1 71.5 1.0
OD2 C:ASP471 4.3 89.5 1.0
CG C:LEU467 4.4 88.2 1.0
CD2 C:LEU467 4.4 88.2 1.0
CD1 C:LEU447 4.5 74.6 1.0
CG1 C:ILE464 4.5 86.7 1.0
CG C:ASP471 4.6 89.5 1.0
N C:LEU467 4.6 88.2 1.0
CG1 C:VAL468 4.7 87.5 1.0
CB C:ASP471 4.7 89.5 1.0
C C:VAL468 4.8 87.5 1.0

Fluorine binding site 6 out of 6 in 9jvw

Go back to Fluorine Binding Sites List in 9jvw
Fluorine binding site 6 out of 6 in the Overall Structure of Human EAAT2 Bound with Inhibitor (Way-213613)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Overall Structure of Human EAAT2 Bound with Inhibitor (Way-213613) within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F1002

b:71.5
occ:1.00
F4 C:GJ01002 0.0 71.5 1.0
C3 C:GJ01002 1.4 71.5 1.0
C2 C:GJ01002 2.3 71.5 1.0
C5 C:GJ01002 2.4 71.5 1.0
F1 C:GJ01002 2.5 71.5 1.0
CG C:MET450 2.8 75.6 1.0
OH C:TYR404 3.2 75.7 1.0
C25 C:GJ01002 3.6 71.5 1.0
C6 C:GJ01002 3.7 71.5 1.0
SD C:MET450 3.7 75.6 1.0
CB C:MET450 3.8 75.6 1.0
CD2 C:LEU467 3.8 88.2 1.0
CE C:MET450 4.0 75.6 1.0
CB C:LEU467 4.1 88.2 1.0
C23 C:GJ01002 4.1 71.5 1.0
CZ C:TYR404 4.2 75.7 1.0
CG1 C:ILE464 4.2 86.7 1.0
CD1 C:ILE464 4.4 86.7 1.0
CE2 C:TYR404 4.5 75.7 1.0
CG C:LEU467 4.5 88.2 1.0
CD1 C:LEU447 4.7 74.6 1.0
O7 C:GJ01002 4.9 71.5 1.0
O C:GLY446 4.9 81.2 1.0

Reference:

L.Y.Xia, Y.Y.Zhang, Y.Shi, J.Huang, Q.Zhou. Structural Study of Human Glutamate Transporter EAAT2 Dian Zi Xian Wei Xue Bao 2025.
ISSN: ISSN 1000-6281
Page generated: Wed Jul 16 11:45:01 2025

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