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Atomistry » Fluorine » PDB 461d-4azy » 4at4 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 461d-4azy » 4at4 » |
Fluorine in PDB 4at4: Crystal Structure of Trkb Kinase Domain in Complex with EX429Enzymatic activity of Crystal Structure of Trkb Kinase Domain in Complex with EX429
All present enzymatic activity of Crystal Structure of Trkb Kinase Domain in Complex with EX429:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of Trkb Kinase Domain in Complex with EX429, PDB code: 4at4
was solved by
T.Bertrand,
M.Kothe,
J.Liu,
A.Dupuy,
A.Rak,
P.F.Berne,
S.Davis,
T.Gladysheva,
C.Valtre,
J.Y.Crenne,
M.Mathieu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Trkb Kinase Domain in Complex with EX429
(pdb code 4at4). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Crystal Structure of Trkb Kinase Domain in Complex with EX429, PDB code: 4at4: Jump to Fluorine binding site number: 1; 2; 3; 4; Fluorine binding site 1 out of 4 in 4at4Go back to Fluorine Binding Sites List in 4at4
Fluorine binding site 1 out
of 4 in the Crystal Structure of Trkb Kinase Domain in Complex with EX429
Mono view Stereo pair view
Fluorine binding site 2 out of 4 in 4at4Go back to Fluorine Binding Sites List in 4at4
Fluorine binding site 2 out
of 4 in the Crystal Structure of Trkb Kinase Domain in Complex with EX429
Mono view Stereo pair view
Fluorine binding site 3 out of 4 in 4at4Go back to Fluorine Binding Sites List in 4at4
Fluorine binding site 3 out
of 4 in the Crystal Structure of Trkb Kinase Domain in Complex with EX429
Mono view Stereo pair view
Fluorine binding site 4 out of 4 in 4at4Go back to Fluorine Binding Sites List in 4at4
Fluorine binding site 4 out
of 4 in the Crystal Structure of Trkb Kinase Domain in Complex with EX429
Mono view Stereo pair view
Reference:
T.Bertrand,
M.Kothe,
J.Liu,
A.Dupuy,
A.Rak,
P.F.Berne,
S.Davis,
T.Gladysheva,
C.Valtre,
J.Y.Crenne,
M.Mathieu.
The Crystal Structures of Trka and Trkb Suggest Key Regions For Achieving Selective Inhibition. J.Mol.Biol. V. 423 439 2012.
Page generated: Sun Dec 13 11:58:55 2020
ISSN: ISSN 0022-2836 PubMed: 22902478 DOI: 10.1016/J.JMB.2012.08.002 |
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