Fluorine in PDB 4u22: GLUA2FLIP Slbd Complexed with Fw and (R,R)-2B Crystal Form D

The structure of GLUA2FLIP Slbd Complexed with Fw and (R,R)-2B Crystal Form D, PDB code: 4u22 was solved by L.Chen, E.Gouaux, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.29 / 1.44
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	64.170, 91.740, 48.090, 90.00, 90.00, 90.00
R / Rfree (%)	18.8 / 21.7

The binding sites of Fluorine atom in the GLUA2FLIP Slbd Complexed with Fw and (R,R)-2B Crystal Form D (pdb code 4u22). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the GLUA2FLIP Slbd Complexed with Fw and (R,R)-2B Crystal Form D, PDB code: 4u22:

Fluorine binding site 1 out of 1 in the GLUA2FLIP Slbd Complexed with Fw and (R,R)-2B Crystal Form D


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of GLUA2FLIP Slbd Complexed with Fw and (R,R)-2B Crystal Form D within 5.0Å range: probe atom residue distance (Å) B Occ A:F401 b:12.5 occ:1.00 F5 A:FWD401 0.0 12.5 1.0 C5 A:FWD401 1.3 10.6 1.0 C6 A:FWD401 2.4 10.4 1.0 C4 A:FWD401 2.4 12.8 1.0 O4 A:FWD401 2.8 12.4 1.0 O A:HOH661 3.1 12.7 1.0 CE A:MET196 3.1 7.6 1.0 OG1 A:THR174 3.3 10.8 1.0 SD A:MET196 3.5 8.7 1.0 CG A:MET196 3.5 8.0 1.0 N1 A:FWD401 3.6 6.5 1.0 N3 A:FWD401 3.7 6.7 1.0 C2 A:FWD401 4.1 6.3 1.0 OE1 A:GLU13 4.1 16.3 1.0 OE1 A:GLU193 4.1 6.2 1.0 CB A:MET196 4.2 7.0 1.0 OE2 A:GLU13 4.3 11.5 1.0 CD A:GLU13 4.3 15.7 1.0 CB A:THR174 4.5 8.6 1.0 OH A:TYR61 4.6 11.1 1.0 N A:GLU193 4.6 4.0 1.0 CB A:GLU193 4.6 5.5 1.0 CG2 A:THR174 4.6 11.5 1.0 CD2 A:LEU138 4.7 13.4 1.0 CD A:GLU193 4.7 5.7 1.0 C7 A:FWD401 4.8 5.7 1.0 CG A:GLU193 4.8 5.3 1.0 CB A:LEU192 5.0 5.6 1.0

K.L.Durr, L.Chen, R.A.Stein, R.De Zorzi, I.M.Folea, T.Walz, H.S.Mchaourab, E.Gouaux. Structure and Dynamics of Ampa Receptor GLUA2 in Resting, Pre-Open, and Desensitized States. Cell V. 158 778 2014.
ISSN: ISSN 1097-4172
PubMed: 25109876
DOI: 10.1016/J.CELL.2014.07.023