Fluorine in PDB 6b24: Crystal Structure of Fluoride Channel Fluc EC2 F80Y Mutant

Protein crystallography data

The structure of Crystal Structure of Fluoride Channel Fluc EC2 F80Y Mutant, PDB code: 6b24 was solved by N.B.Last, S.Sun, M.C.Pham, C.Miller, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 42.65 / 2.75
Space group P 41
Cell size a, b, c (Å), α, β, γ (°) 88.400, 88.400, 146.070, 90.00, 90.00, 90.00
R / Rfree (%) 22.5 / 25.2

Other elements in 6b24:

The structure of Crystal Structure of Fluoride Channel Fluc EC2 F80Y Mutant also contains other interesting chemical elements:

Sodium (Na) 1 atom

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Crystal Structure of Fluoride Channel Fluc EC2 F80Y Mutant (pdb code 6b24). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Crystal Structure of Fluoride Channel Fluc EC2 F80Y Mutant, PDB code: 6b24:
Jump to Fluorine binding site number: 1; 2; 3; 4;

Fluorine binding site 1 out of 4 in 6b24

Go back to Fluorine Binding Sites List in 6b24
Fluorine binding site 1 out of 4 in the Crystal Structure of Fluoride Channel Fluc EC2 F80Y Mutant


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of Fluoride Channel Fluc EC2 F80Y Mutant within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F202

b:85.2
occ:1.00
O B:ASN41 2.7 86.6 1.0
OG B:SER110 2.9 90.7 1.0
N A:SER81 3.3 79.8 1.0
C A:TYR80 3.4 79.0 1.0
CA A:SER81 3.4 81.0 1.0
N B:GLY45 3.4 88.4 1.0
O A:TYR80 3.4 78.2 1.0
CB A:TYR80 3.7 80.0 1.0
CA B:GLY45 3.7 88.2 1.0
C B:ASN41 3.7 87.0 1.0
OG A:SER84 3.9 87.9 1.0
CD1 A:TYR80 4.0 81.7 1.0
CB A:SER81 4.0 84.4 1.0
CA B:ASN41 4.1 86.0 1.0
C B:ALA44 4.1 89.1 1.0
CB B:ALA44 4.1 89.0 1.0
CA A:TYR80 4.1 78.7 1.0
CB B:SER110 4.2 90.5 1.0
CG A:TYR80 4.3 80.6 1.0
CB B:ASN41 4.4 84.5 1.0
CB B:SER78 4.4 77.8 1.0
CA B:ALA44 4.6 90.1 1.0
CB A:SER84 4.6 86.9 1.0
C A:SER81 4.7 79.8 1.0
O B:ALA44 4.7 89.7 1.0
OD1 B:ASN41 4.8 84.3 1.0
N B:LEU42 4.9 85.6 1.0
CG B:ASN41 4.9 84.3 1.0
O A:SER81 5.0 81.1 1.0

Fluorine binding site 2 out of 4 in 6b24

Go back to Fluorine Binding Sites List in 6b24
Fluorine binding site 2 out of 4 in the Crystal Structure of Fluoride Channel Fluc EC2 F80Y Mutant


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Crystal Structure of Fluoride Channel Fluc EC2 F80Y Mutant within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F203

b:0.1
occ:1.00
OE1 A:GLU86 2.6 85.3 1.0
O A:HOH302 2.6 99.8 1.0
CB A:GLU86 3.3 84.5 1.0
O A:HOH303 3.4 87.7 1.0
O A:PHE83 3.5 75.9 1.0
CD A:GLU86 3.7 84.8 1.0
CD1 A:PHE83 3.7 79.0 1.0
NE2 A:HIS106 3.8 85.5 1.0
CB A:SER102 3.9 88.7 1.0
CG2 A:VAL87 4.0 75.9 1.0
CD2 A:HIS106 4.0 84.0 1.0
CA A:PHE83 4.0 79.8 1.0
CG A:GLU86 4.1 85.1 1.0
C A:PHE83 4.2 79.7 1.0
OG A:SER102 4.2 90.7 1.0
N A:VAL87 4.3 79.2 1.0
CE1 A:PHE83 4.3 80.7 1.0
CA A:GLU86 4.5 82.5 1.0
CG A:PHE83 4.6 77.9 1.0
C A:GLU86 4.6 81.2 1.0
CE1 A:HIS106 4.6 85.3 1.0
CD A:PRO34 4.7 86.1 1.0
CB A:PHE83 4.7 78.6 1.0
OE2 A:GLU86 4.8 84.9 1.0
O A:THR82 4.8 79.0 1.0
CD1 A:LEU33 4.8 87.7 1.0
CG A:HIS106 5.0 82.6 1.0

Fluorine binding site 3 out of 4 in 6b24

Go back to Fluorine Binding Sites List in 6b24
Fluorine binding site 3 out of 4 in the Crystal Structure of Fluoride Channel Fluc EC2 F80Y Mutant


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Crystal Structure of Fluoride Channel Fluc EC2 F80Y Mutant within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F202

b:73.2
occ:1.00
OG A:SER110 2.8 88.3 1.0
O A:ASN41 2.8 79.8 1.0
C B:TYR80 3.3 74.7 1.0
O B:TYR80 3.3 73.5 1.0
N B:SER81 3.3 76.2 1.0
CA B:SER81 3.4 77.5 1.0
N A:GLY45 3.5 79.4 1.0
CB B:TYR80 3.6 76.0 1.0
OG B:SER84 3.7 84.1 1.0
CA A:GLY45 3.8 77.2 1.0
C A:ASN41 3.8 79.9 1.0
CD1 B:TYR80 3.8 76.0 1.0
CB A:SER110 4.0 85.1 1.0
CA B:TYR80 4.1 74.8 1.0
CB B:SER81 4.1 79.0 1.0
CG B:TYR80 4.2 76.5 1.0
CA A:ASN41 4.2 80.5 1.0
C A:ALA44 4.2 81.0 1.0
CB A:ALA44 4.3 80.7 1.0
CB A:ASN41 4.4 78.5 1.0
CB B:SER84 4.5 82.3 1.0
CB A:SER78 4.5 79.6 1.0
C B:SER81 4.6 77.7 1.0
CA A:ALA44 4.8 80.7 1.0
OD1 A:ASN41 4.9 79.8 1.0
O A:ALA44 4.9 83.8 1.0
O B:SER81 4.9 78.5 1.0
CE1 B:TYR80 4.9 77.5 1.0
CG A:ASN41 5.0 79.4 1.0
N A:LEU42 5.0 78.3 1.0

Fluorine binding site 4 out of 4 in 6b24

Go back to Fluorine Binding Sites List in 6b24
Fluorine binding site 4 out of 4 in the Crystal Structure of Fluoride Channel Fluc EC2 F80Y Mutant


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Crystal Structure of Fluoride Channel Fluc EC2 F80Y Mutant within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F203

b:77.9
occ:1.00
OE1 B:GLU86 2.7 81.7 1.0
O B:HOH303 3.1 0.2 1.0
CB B:GLU86 3.1 81.2 1.0
O B:PHE83 3.3 77.1 1.0
O B:HOH301 3.6 89.5 1.0
CD B:GLU86 3.7 82.7 1.0
CD1 B:PHE83 3.7 76.6 1.0
CG2 B:VAL87 3.8 78.9 1.0
NE2 B:HIS106 3.9 80.3 1.0
CB B:SER102 3.9 85.8 1.0
CG B:GLU86 4.0 82.2 1.0
CA B:PHE83 4.0 76.8 1.0
C B:PHE83 4.1 77.2 1.0
N B:VAL87 4.1 78.5 1.0
CD2 B:HIS106 4.1 81.4 1.0
OG B:SER102 4.2 86.2 1.0
CA B:GLU86 4.3 81.0 1.0
CE1 B:PHE83 4.3 77.9 1.0
C B:GLU86 4.4 81.1 1.0
CG B:PHE83 4.6 76.2 1.0
O B:THR82 4.7 74.2 1.0
CB B:PHE83 4.7 77.3 1.0
CE1 B:HIS106 4.8 80.4 1.0
CD B:PRO34 4.8 86.7 1.0
OE2 B:GLU86 4.8 82.8 1.0
CA B:VAL87 4.9 78.2 1.0
CB B:VAL87 4.9 78.4 1.0
N B:GLU86 5.0 80.4 1.0
CD1 B:LEU33 5.0 89.2 1.0

Reference:

N.B.Last, S.Sun, M.C.Pham, C.Miller. Molecular Determinants of Permeation in A Fluoride-Specific Ion Channel. Elife V. 6 2017.
ISSN: ESSN 2050-084X
PubMed: 28952925
DOI: 10.7554/ELIFE.31259
Page generated: Sun Dec 13 12:44:53 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy