|
Fluorine in PDB 7qc5: Crystal Structure of Human Wild Type Transthyretin in Complex with (3, 4-Dihydroxy-5-Nitrophenyl)-(3-Fluoro-5-Hydroxyphenyl)Methanone CompoundProtein crystallography data
The structure of Crystal Structure of Human Wild Type Transthyretin in Complex with (3, 4-Dihydroxy-5-Nitrophenyl)-(3-Fluoro-5-Hydroxyphenyl)Methanone Compound, PDB code: 7qc5
was solved by
N.Varejao,
F.Pinheiro,
I.Pallares,
S.Ventura,
D.Reverter,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Human Wild Type Transthyretin in Complex with (3, 4-Dihydroxy-5-Nitrophenyl)-(3-Fluoro-5-Hydroxyphenyl)Methanone Compound
(pdb code 7qc5). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of Human Wild Type Transthyretin in Complex with (3, 4-Dihydroxy-5-Nitrophenyl)-(3-Fluoro-5-Hydroxyphenyl)Methanone Compound, PDB code: 7qc5: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 7qc5Go back to Fluorine Binding Sites List in 7qc5
Fluorine binding site 1 out
of 2 in the Crystal Structure of Human Wild Type Transthyretin in Complex with (3, 4-Dihydroxy-5-Nitrophenyl)-(3-Fluoro-5-Hydroxyphenyl)Methanone Compound
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 7qc5Go back to Fluorine Binding Sites List in 7qc5
Fluorine binding site 2 out
of 2 in the Crystal Structure of Human Wild Type Transthyretin in Complex with (3, 4-Dihydroxy-5-Nitrophenyl)-(3-Fluoro-5-Hydroxyphenyl)Methanone Compound
Mono view Stereo pair view
Reference:
F.Pinheiro,
I.Pallares,
F.Peccati,
A.Sanchez-Morales,
N.Varejao,
F.Bezerra,
D.Ortega-Alarcon,
D.Gonzalez,
M.Osorio,
S.Navarro,
A.Velazquez-Campoy,
M.R.Almeida,
D.Reverter,
F.Busque,
R.Alibes,
M.Sodupe,
S.Ventura.
Development of A Highly Potent Transthyretin Amyloidogenesis Inhibitor: Design, Synthesis, and Evaluation. J.Med.Chem. V. 65 14673 2022.
Page generated: Wed Apr 5 00:40:12 2023
ISSN: ISSN 0022-2623 PubMed: 36306808 DOI: 10.1021/ACS.JMEDCHEM.2C01195 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |