Atomistry » Fluorine » PDB 7fw1-7g2n
Atomistry »
  Fluorine »
    PDB 7fw1-7g2n »
      7fw1 »
      7fw7 »
      7fwd »
      7fwf »
      7fwj »
      7fwz »
      7fx2 »
      7fx5 »
      7fxg »
      7fxs »
      7fxy »
      7fy8 »
      7fy9 »
      7fyf »
      7fyh »
      7fyq »
      7fyy »
      7fz2 »
      7fz4 »
      7fzh »
      7g03 »
      7g05 »
      7g0i »
      7g0t »
      7g0v »
      7g18 »
      7g1h »
      7g1i »
      7g1k »
      7g1p »
      7g2e »
      7g2f »
      7g2g »
      7g2h »
      7g2i »
      7g2j »
      7g2k »
      7g2l »
      7g2m »
      7g2n »

Fluorine in PDB, part 186 (files: 7401-7440), PDB 7fw1-7g2n

Experimental structures of coordination spheres of Fluorine (F) in bioorganic molecules from X-Ray and NMR experiments. Coordination spheres were calculated with 5.0 Angstroms radius around Fluorine atoms. PDB files: 7401-7440 (PDB 7fw1-7g2n).
  1. 7fw1 (F: 1) - Crystal Structure of Human FABP4 in Complex with 2-Cyclopentyl-4-(4- Fluorophenyl)-6-[1-(Methoxymethyl)Cyclopentyl]-3-Methyl-5-(1H- Tetrazol-5-Yl)Pyridine
  2. 7fw7 (F: 1) - Crystal Structure of Human FABP4 in Complex with 2-[(3-Chloro-4- Fluorophenyl)Carbamoyl]Cyclohexane-1-Carboxylic Acid
    Other atoms: Cl (1);
  3. 7fwd (F: 1) - Crystal Structure of Human FABP4 in Complex with 3-[1-(4- Carbamoylphenyl)-5-(4-Fluorophenyl)Pyrrol-2-Yl]Propanoic Acid
  4. 7fwf (F: 6) - Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 5-Cyclohexyl-6-(2,2,2-Trifluoroethoxy)-2- (Trifluoromethyl)Pyridine-3-Carboxylic Acid
  5. 7fwj (F: 6) - Crystal Structure of Human FABP4 in Complex with 5-Cyclohexyl-6-(2,2, 2-Trifluoroethoxy)-2-(Trifluoromethyl)Pyridine-3-Carboxylic Acid
  6. 7fwz (F: 3) - Crystal Structure of Human FABP4 in Complex with 4-[3- (Trifluoromethyl)-5,6,7,8-Tetrahydro-4H-Cyclohepta[C]Pyrazol-1- Yl]Butanoic Acid
  7. 7fx2 (F: 4) - Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 2-[[6,6-Difluoro-3-(4-Methyl-1,3-Thiazol-2-Yl)-5,7- Dihydro-4H-1-Benzothiophen-2-Yl]Carbamoyl]Cyclohexene-1-Carboxylic Acid
  8. 7fx5 (F: 2) - Crystal Structure of Human FABP4 in Complex with 5-[[3-(3-Cyclopropyl- 1,2,4-Oxadiazol-5-Yl)-6,6-Difluoro-5,7-Dihydro-4H-1-Benzothiophen-2- Yl]Carbamoyl]-3,6-Dihydro-2H-Pyran-4-Carboxylic Acid
    Other atoms: Cl (1);
  9. 7fxg (F: 12) - Crystal Structure of Human FABP4 in Complex with 2-Chloro-4,6- Bis(Trifluoromethylsulfanyl)Phenol
    Other atoms: Cl (3);
  10. 7fxs (F: 6) - Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 5-Phenoxy-6-(2,2,2-Trifluoroethoxy)-2- (Trifluoromethyl)Pyridine-3-Carboxylic Acid
  11. 7fxy (F: 2) - Crystal Structure of Human FABP4 in Complex with (4-Chlorophenyl) Methyl 5-Fluoro-2,4-Dioxo-1H-Pyrimidine-6-Carboxylate
    Other atoms: Cl (2);
  12. 7fy8 (F: 24) - Crystal Structure of Human FABP1 in Complex with 2-[[4-Cyclopropyl-5- Methyl-3-[3-(Trifluoromethyl)-1,2,4-Oxadiazol-5-Yl]Thiophen-2- Yl]Carbamoyl]Cyclopentene-1-Carboxylic Acid
  13. 7fy9 (F: 1) - Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 2-Cyclopentyl-4-(4-Fluorophenyl)-6-[1- (Methoxymethyl)Cyclopentyl]-3-Methyl-5-(1H-Tetrazol-5-Yl)Pyridine
  14. 7fyf (F: 1) - Crystal Structure of Human FABP4 in Complex with 4-(4-Fluorophenyl)-2- Piperidin-1-Yl-3-(1H-Tetrazol-5-Yl)-7,8-Dihydro-5H-Pyrano[4,3- B]Pyridine
  15. 7fyh (F: 1) - Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 6-Fluoro-1,3-Benzothiazol-2-Amine
  16. 7fyq (F: 6) - Crystal Structure of Human FABP4 in Complex with 2-(3,5-Ditert-Butyl- 2-Hydroxyphenyl)-3,3,3-Trifluoro-2-Hydroxypropanoic Acid
  17. 7fyy (F: 12) - Crystal Structure of Human FABP4 in Complex with 5,7- Bis(Trifluoromethylsulfanyl)Quinolin-8-Ol
  18. 7fz2 (F: 6) - Crystal Structure of Human FABP4 in Complex with [3-Oxo-5-[4- (Trifluoromethyl)Phenyl]Cyclohexen-1-Yl] Acetate
  19. 7fz4 (F: 5) - Crystal Structure of Human FABP4 in Complex with 6-(Difluoromethyl)-4- Isobutyl-5-Methoxycarbonyl-2-(Trifluoromethyl)Pyridine-3-Carboxylic Acid
  20. 7fzh (F: 2) - Crystal Structure of Human FABP4 in Complex with 4-[[3-(3-Cyclopropyl- 1,2,4-Oxadiazol-5-Yl)-6,6-Difluoro-5,7-Dihydro-4H-1-Benzothiophen-2- Yl]Carbamoyl]-3,6-Dihydro-2H-Pyran-5-Carboxylic Acid
    Other atoms: Cl (1);
  21. 7g03 (F: 1) - Crystal Structure of Human FABP4 in Complex with 6-Fluoro-1,3- Benzothiazol-2-Amine
  22. 7g05 (F: 6) - Crystal Structure of Human FABP4 in Complex with 2,6-Dichloro-4-(1,1, 1,3,3,3-Hexafluoro-2-Hydroxypropan-2-Yl)Phenol
    Other atoms: Cl (2);
  23. 7g0i (F: 6) - Crystal Structure of Human FABP4 in Complex with 5-Phenoxy-6-(2,2,2- Trifluoroethoxy)-2-(Trifluoromethyl)Pyridine-3-Carboxylic Acid
  24. 7g0t (F: 3) - Crystal Structure of Human FABP4 in Complex with 1-[[4-Chloro-2- (Trifluoromethyl)Phenyl]Carbamoylamino]Cyclopentane-1-Carboxylic Acid
    Other atoms: Cl (1);
  25. 7g0v (F: 3) - Crystal Structure of Human FABP4 in Complex with Rac-(1R,2S)-2-[[3- (Trifluoromethyl)Phenoxy]Methyl]Cyclohexane-1-Carboxylic Acid
  26. 7g18 (F: 2) - Crystal Structure of Human FABP4 in Complex with 4-(4-Chloro-3- Fluorophenoxy)-2-(3,4-Dichlorophenyl)-2-Methylbutanoic Acid
    Other atoms: Cl (6);
  27. 7g1h (F: 6) - Crystal Structure of Human FABP4 in Complex with 2-(3,5-Ditert-Butyl- 2-Hydroxyphenyl)-3,3,3-Trifluoro-2-Hydroxypropanoic Acid
  28. 7g1i (F: 6) - Crystal Structure of Human FABP4 in Complex with 5-(4-Chlorophenyl)-6- (2,2,2-Trifluoroethoxy)-2-(Trifluoromethyl)Pyridine-3-Carboxylic Acid
    Other atoms: Cl (1);
  29. 7g1k (F: 2) - Crystal Structure of Human FABP4 in Complex with 4-(4-Fluorophenyl) Sulfanyl-6-Methyl-2-Phenylpyrimidine-5-Carboxylic Acid
  30. 7g1p (F: 1) - Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 6-Chloro-5-Fluoro-1H-Benzimidazole
    Other atoms: Cl (1);
  31. 7g2e (F: 1) - Crystal Structure of Rat Autotaxin in Complex with 2-(3,4- Dichlorophenyl)-1-[4-[(4-Fluorophenyl)Methyl]-7,8-Dihydro-5H- Pyrido[4,3-D]Pyrimidin-6-Yl]Ethanone, I.E. Smiles FC1CCC(CC1) CC1C2CN(C(=O)CC3CCC(Cl)C(Cl)C3)CCC2NCN1 with IC50=0.795943 Microm
    Other atoms: Zn (1); Cl (2); Ca (2); Na (2);
  32. 7g2f (F: 3) - Crystal Structure of Rat Autotaxin in Complex with 4-[4-[3-[2-[(5- Methyltetrazol-2-Yl)Methyl]-4-(Trifluoromethyl) Phenyl]Propanoyl]Piperazin-1-Yl]Sulfonylbenzenesulfonamide, I.E. Smiles Fc(C1CC(C(Ccc(=O)N2CCN(CC2)S(=O)(=O)C2CCC(S(=O)(=O)N)CC2)CC1) CN1N=Nc(=N1)C)(F)F with IC50=0.0525995 Microm
    Other atoms: Ca (1); K (1); Zn (1); Cl (1);
  33. 7g2g (F: 4) - Crystal Structure of Rat Autotaxin in Complex with 3-Fluoro-4-[[4-[3- [2-[(5-Methyltetrazol-2-Yl)Methyl]-4-(Trifluoromethyl) Phenyl]Propanoyl]Piperazin-1-Yl]Methyl]Benzenesulfonamide, I.E. Smiles N1(Ccn(CC1)CC1C(Cc(S(=O)(=O)N)CC1)F)C(=O) CCC1CCC(CC1CN1N=Nc(=N1)C)C(F)(F)F with IC50=0.0203648 Microm
    Other atoms: Na (1); Ca (2); K (1); Cl (1); Zn (1);
  34. 7g2h (F: 4) - Crystal Structure of Rat Autotaxin in Complex with 3-Fluoro-4-[1-[3- [2-[(5-Methyltetrazol-2-Yl)Methyl]-4-(Trifluoromethyl) Phenyl]Propanoyl]Piperidin-4-Yl]Sulfonylbenzenesulfonamide, I.E. Smiles O=C(N1CC[C@@H](S(=O)(=O)C2C(F)Cc(S(=O)(=O)N)CC2)CC1) CCC1CCC(CC1CN1N=Nc(=N1)C)C(F)(F)F with IC50=0.00379624 Microm
    Other atoms: Zn (1); K (1); Ca (1); Na (1);
  35. 7g2i (F: 4) - Crystal Structure of Rat Autotaxin in Complex with 3-Fluoro-4-[2-[1- [3-[2-[(5-Methyltetrazol-2-Yl)Methyl]-4-(Trifluoromethyl) Phenyl]Propanoyl]Piperidin-4-Yl]Ethylsulfonyl]Benzenesulfonamide, I.E. Smiles C1(S(=O)(=O)Cc[C@H]2CCN(C(=O)CCC3C(CN4N=C(C)N=N4)Cc(C(F) (F)F)CC3)CC2)Ccc(S(=O)(=O)N)CC1F with IC50=0.00184303 Microm
    Other atoms: Ca (2); Na (2); Cl (1); Zn (1);
  36. 7g2j (F: 1) - Crystal Structure of Rat Autotaxin in Complex with 2-Chloro-5-(5- Cyclopropyloxy-2-Fluorophenyl)-4-(1H-Pyrazolo[3,4-B]Pyridin-3- Ylmethoxy)Benzonitrile, I.E. Smiles C1C(C1)OC1CCC(F)C(C1)C1CC(C#N) C(Cl)CC1OCC1=NNC2NCCCC12 with IC50=0.0201566 Microm
    Other atoms: Na (2); Ca (2); Zn (1); Cl (1);
  37. 7g2k (F: 1) - Crystal Structure of Rat Autotaxin in Complex with 2-Chloro-5-(5- Cyclopropyloxy-2-Fluorophenyl)-4-[(4-Methyl-5-Oxo-1H-1,2,4-Triazol-3- Yl)Methoxy]Benzonitrile, I.E. Smiles C1C(Ccc(C1C1CC(C(Cl) CC1OCC1=Nnc(=O)N1C)C#N)F)OC1CC1 with IC50=0.0091413 Microm
    Other atoms: Ca (2); Na (2); Zn (1); Cl (1);
  38. 7g2l (F: 1) - Crystal Structure of Rat Autotaxin in Complex with 2-Chloro-5-(5- Cyclopropyloxy-2-Fluorophenyl)-4-(1H-Pyrazolo[3,4-C]Pyridin-3- Ylmethoxy)Benzonitrile, I.E. Smiles C1C(C1)OC1CCC(F)C(C1)C1CC(C#N) C(Cl)CC1OCC1=NNC2CNCCC12 with IC50=0.787674 Microm
    Other atoms: Cl (1); Zn (1); Ca (2); Na (2);
  39. 7g2m (F: 4) - Crystal Structure of Rat Autotaxin in Complex with 5-Fluoro-6-[2-[3- [2-[(5-Methyltetrazol-2-Yl)Methyl]-4-(Trifluoromethyl) Phenyl]Propanoyl]-1,3,4,6-Tetrahydropyrrolo[3,4-C]Pyrrole-5- Carbonyl]Pyridine-3-Sulfonamide, I.E. Smiles C12=C(Cn(C1)C(=O) CCC1CCC(CC1CN1N=Nc(=N1)C)C(F)(F)F)Cn(C2)C(=O)C1NCC(CC1F)S(=O)(=O)N with IC50=0.0018642 Microm
    Other atoms: Na (2); Ca (1); Cl (1); Zn (1);
  40. 7g2n (F: 4) - Crystal Structure of Rat Autotaxin in Complex with 5-Fluoro-6-[1-[3- [2-[(5-Methyltetrazol-2-Yl)Methyl]-4-(Trifluoromethyl) Phenyl]Propanoyl]Piperidin-4-Yl]Sulfanylpyridine-3-Sulfonamide, I.E. Smiles O=C(N1CC[C@@H](SC2C(F)Cc(S(=O)(=O)N)CN2)CC1) CCC1CCC(CC1CN1N=Nc(=N1)C)C(F)(F)F with IC50=0.00881095 Microm
    Other atoms: Zn (1); Na (2); Ca (2);
Page generated: Sat Feb 15 17:03:00 2025

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy